Figure 2.

CENPU enhanced the growth and migration of hepatoma cells. (A-B) The efficiency of CENPU knockdown and overexpression was validated via qRT-PCR and immunoblotting. (C-D) The proliferative ability of Huh-7, MHCC-97H, and HCCLM3 cells was detected by CCK-8 and colony formation assays. (E-F) CENPU knockdown repressed the invasion and migration ability of Huh-7 and MHCC-97H cells, while CENPU overexpression reversed these results in HCCLM3 cells. (G) EdU assays indicating that CENPU silencing delayed the G1/S transition. *p < 0.05; **p < 0.01; ***p < 0.001.