Figure 1.

Eplerenone improved the short-term working memory impairment of SHRs in a Y maze test. A. There was no significant difference in total arm entries among the four groups. B. Bar graph showing the increased correct spontaneous alternation of SHRs in the SHR-EPL30 group and SHR-EPL100 group. Data are expressed as mean ± SD, N = 12. Significance was determined using one-way analysis of variance (one-way ANOVA) followed by Tukey’s post hoc test, ***P < 0.001 vs. SHR-Veh. SHR: spontaneous hypertensive rat. WKY: Wistar Kyoto rat.