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HNF1A-AS1 promotes colorectal cancer cell migration, invasion, and proliferation. In colorectal cancer, HNF1A-AS1 enhances cell proliferation, invasion, and migration by repressing miR-34a/SIRT1/p53 signaling and activating the Wnt/β-catenin signaling pathway; interacting with PBX3 and increasing OTX1 to activate the ERK/MAPK pathway; or sponging miR-124 and upregulating MYO6.
