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. 2022 Jun 15;14(6):4154–4168.

Table 1.

The expression and clinical characteristics of HNF1A-AS1 in human cancers

Disease type Expression Clinical characteristics Refs
gastric cancer upregulated lymph node metastasis [26-28]
downregulated tumor size, levels of serum carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), and RRM1 expression [24]
gastric cancer upregulated / [28]
liver cancer upregulated tumor size, tumor stage, multiple lesions, and poor differentiation [29-31]
downregulated / [23]
glioma upregulated overall survival [32-34]
lung cancer upregulated overall survival, pathological stage, TNM stage, tumor size, and lymph node metastasis [35-39]
colorectal cancer upregulated tumor size, TNM stage, lymph nodes metastasis, distant metastasis, overall survival, disease-free survival, and vascular invasion [40-44]
colorectal cancer upregulated / [88]
breast cancer upregulated overall survival [45-47]
bladder cancer upregulated histological grade, TNM stage, lymph nodes metastasis, and overall survival [48-50]
osteosarcoma upregulated clinical stage, distance metastasis, chemotherapy resistance, and poor overall survival [51-53]
cervical cancer upregulated / [56,57]
esophageal adenocarcinoma upregulated / [25]
hemangioma upregulated [54]
oral squamous cell carcinoma upregulated nodal invasion, tumor stage, and tissue differentiation [55]
laryngeal squamous cell carcinoma downregulated / [22]
gastroenteropancreatic neuroendocrine neoplasms downregulated / [58]