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. 2022 Jun 22;8(7):1356–1366. doi: 10.1021/acsinfecdis.2c00232

Table 5. Effect of 1720 in NTS.

    percentage of NTS activity, 72 h
 
lab code compd 20 μM 10 μM 1 μM IC50 (μM)
MC2776 17 100.0 ± 0.0 100.0 ± 0.0 28.0 ± 0.0 1.23
MC2779 18 100.0 ± 0.0 100.0 ± 0.0 26.0 ± 1.0 1.26
MC2778 19 100.0 ± 0.0 100.0 ± 0.0 24.0 ± 0.0 1.29
MC2783 20 100.0 ± 0.0 100.0 ± 0.0 22.0 ± 1.0 1.32