Skip to main content
. 2022 Jul 12;10(8):e627. doi: 10.1002/iid3.627

Figure 2.

Figure 2

NEF regulated the expression of inflammatory factors in human fibroblast‐like synovial (HFLS). HFLS cells were obtained from ankylosing spondylitis patients and transfected with NEF overexpression plasmid, si‐NEF, or their negative controls (pcDNA or si‐con). The protein levels of interleukin‐1β (IL‐1β), interleukin‐6 (IL‐6), and tumor necrosis factor‐α (TNF‐α) in these cells were detected by Western blot. LncRNA‐NEF overexpression promoted the expression of inflammatory factors, while lncRNA‐NEF knockdown inhibited the expression of inflammatory factors. *p < .05.