Figure 2.

Stage 2 mega-analysis results. (a) Manhattan plot of Stage 2 GWAS mega-analysis of NACC and ROSMAP. The horizontal dashed line in each plot is the suggestive threshold (p <  $1\times {10}^{-5}$ ) while the solid line is the threshold for genome-wide significance (p <  $5\times {10}^{-8}$ ). (b & c) Regional plots of rs2603462 and rs7902929 +/− 1000 kb, respectively.