Table 1.
Unstandardized regression coefficients with physiological confounders for neurovascular coupling metrics produced during a “Where’s Waldo?” paradigm in 60 individuals (30 females/30 males) within the posterior cerebral artery.
| Baseline (cm/s) | Peak (cm/s) | Relative Increase (%) | AUC30 (cm/s/30s) | Time to Peak (s) | |
|---|---|---|---|---|---|
| One Cycle | 1.01 (0.97, 1.05) | 1.05 (1.01, 1.10)* | 1.21 (1.12, 1.30)* | 0.87 (0.74, 1.03) | 0.88 (0.81, 0.96)* |
| Two Cycles | 1.01 (0.97, 1.05) | 1.03 (0.99, 1.08) | 1.12 (1.03, 1.20)* | 1.00 (0.85, 1.19) | 0.94 (0.86, 1.03) |
| Three Cycles | 1.01 (0.97, 1.05) | 1.02 (0.98, 1.07) | 1.08 (1.00, 1.17) | 1.00 (0.85, 1.18) | 0.97 (0.89, 1.06) |
| Four Cycles | 1.01 (0.97, 1.05) | 1.02 (0.98, 1.06) | 1.06 (0.98, 1.14) | 1.00 (0.85, 1.18) | 0.97 (0.89, 1.06) |
| Five Cycles | 1.00 (0.97, 1.05) | 1.01 (0.97, 1.06) | 1.04 (0.96, 1.12) | 1.00 (0.85, 1.17) | 0.99 (0.91, 1.08) |
| Six Cycles | 1.00 (0.96, 1.04) | 1.01 (0.97, 1.05) | 1.03 (0.95, 1.11) | 1.00 (0.86, 1.16) | 0.97 (0.89, 1.06) |
| Seven Cycles | 1.00 (0.96, 1.04) | 1.00 (0.96, 1.04) | 1.01 (0.94, 1.09) | 1.00 (0.87, 1.15) | 0.98 (0.90, 1.07) |
| Confounding Variables | PETCO2 and HR | – | MAP and HR | RR, PETCO2, and HR | PETCO2 and HR |
Note: Numerous individuals completed repeated assessments/follow-ups, which produced a total of 160 unique data points. Data were produced from the number of trials completed which ranged from one to eight, which values produced from trials one to seven were compared to the “reference-standard” eight trials. Data are beta coefficient (95% confidence interval). Significant values are displayed in bold with an asterisk (*) (p<0.050). Area-under-the-curve during the first 30 seconds of stimulus onset (AUC30), centimetre (cm), second (s), percent (%), respiratory rate (RR), partial pressure of carbon dioxide (PETCO2), mean arterial pressure (MAP), and heart rate (HR).