Table III.
Quality of life and burden of disease scores in different levels of sociodemographic and clinical variables in 399 adolescents with atopic dermatitis (AD) and their parents
| Variable | EQ-5D VAS Parents Mean ± SD |
p-value | EQ-5D VAS Adolescents Mean ± SD |
p-value | CDLQI Children 12–14 years Mean ± SD |
p-value | DLQI Children 15–17 years Mean ± SD |
p-value | ABS-F Parents Mean ± SD |
p-value |
|---|---|---|---|---|---|---|---|---|---|---|
| Overall | 73.8 ± 21.3 | 72.7 ± 22.2 | 8.7 ± 7.1 | 12.8 ± 11.1 | 10.0 ± 8.0 | |||||
| Severity (POEM) | ||||||||||
| Mild | 77.0 ± 19.8 | 78.2 ± 19.4 | 5.6 ± 5.6 | 6.7 ± 6.8 | 8.6 ± 9.2 | |||||
| Moderate | 72.3 ± 20.8 | 0.02 * | 68.8 ± 21.5 | < 0.001 * | 12.7 ± 7.0 | < 0.001 * | 12.4 ± 7.0 | < 0.001 * | 16.9 ± 10.4 | < 0.001 * |
| Severe | 59.1 ± 25.0 | < 0.001 ** | 51.7 ± 25.4 | < 0.001 ** | 15.9 ± 4.1 | 0.07** | 18.2 ± 6.8 | < 0.001 ** | 24.3 ± 10.2 | < 0.001 ** |
| Sex (child) | ||||||||||
| Boys | 74.0 ± 20.9 | 71.7 ± 22.8 | 9.0 ± 7.4 | 10.5 ± 8.0 | 13.9 ± 11.4 | |||||
| Girls | 73.4 ± 21.8 | 0.77 | 73.9 ± 21.4 | 0.33 | 8.4 ± 6.8 | 0.58 | 9.2 ± 7.8 | 0.27 | 11.4 ± 10.4 | 0.03 |
| Age (child) | ||||||||||
| 12–14.9 years | 75.0 ± 19.1 | 74.6 ± 21.2 | 8.6 ± 7.0 | 11.7 ± 10.2 | ||||||
| 15–17.9 years | 72.6 ± 23.3 | 0.27 | 70.6 ± 23.1 | 0.07 | 10.0 ± 7.9 | 14.1 ± 11.8 | 0.03 | |||
| Duration of the disease | ||||||||||
| < 5 years | 73.4 ± 20.2 | 70.7± 22.4 | 10.0 ± 7.2 | 11.6 ± 8.4 | 14.7 ± 11.4 | |||||
| ≥ 5 years | 74.2 ± 22.5 | 0.72 | 74.6± 21.9 | 0.08 | 7.0 ± 6.7 | 0.003 | 8.7 ± 7.3 | 0.01 | 10.9 ± 10.4 | 0.001 |
| Presence of AD in parents | ||||||||||
| One or both of them | 71.2 ± 21.4 | 70.5± 23.0 | 10.2 ± 7.4 | 11.4 ± 8.4 | 14.5 ± 11.3 | |||||
| None | 76.0± 21.0 | 0.02 | 74.4± 21.4 | 0.08 | 7.4 ± 6.7 | 0.006 | 8.8± 7.4 | 0.02 | 11.4 ± 10.7 | 0.005 |
| Parent | ||||||||||
| Father | 72.9± 21.0 | 66.4± 23.4 | 10.6 ± 6.9 | 13.2 ± 7.9 | 16.8 ± 11.7 | |||||
| Mother | 74.2± 21.5 | 0.58 | 75.6 ± 21.0 | < 0.001 | 8.0 ± 7.1 | 0.02 | 8.1± 7.4 | < 0.001 | 11.0 ± 10.3 | < 0.001 |
| Age (parent) | ||||||||||
| < 45 years | 76.4± 19.3 | 73.8 ± 20.4 | 8.3 ± 6.9 | 10.6 ± 8.0 | 12.6 ± 11.0 | |||||
| ≥ 45 years | 73.1 ± 22.2 | 0.14 | 74.9 ± 23.4 | 0.62 | 8.2 ± 7.4 | 0.90 | 7.9 ± 6.5 | 0.02 | 11.0 ± 10.0 | 0.16 |
| Professional level (parent)*** | ||||||||||
| CSP+ | 74.7 ± 20.7 | 70.9 ± 21.7 | 10.3 ± 7.7 | 10.4 ± 7.8 | 14.0 ± 11.2 | |||||
| CSP− | 73.8 ± 21.9 | 0.68 | 73.9 ± 23.6 | 0.20 | 7.5 ± 6.6 | 0.01 | 9.1 ± 7.7 | 0.24 | 11.8 ± 11.1 | 0.06 |
| Educational sessions on AD (child or parent) | ||||||||||
| Yes | 66.8 ± 24.3 | 59.3 ± 23.6 | 18.0 ± 5.5 | 20.0 ± 7.0 | 25.7 ± 9.1 | |||||
| No | 75.0 ± 20.5 | 0.007 | 74.8 ± 20.5 | < 0.001 | 7.2 ± 6.1 | < 0.001 | 8.2 ± 6.7 | < 0.001 | 10.7 ± 9.8 | < 0.001 |
Moderate vs mild;
Severe vs moderate;
The (+) category included individuals belonging to higher and intermediate managerial, administrative, professional, supervisory, clerical and junior managerial, administrative, and professional occupations; the (−) category included skilled, semi-skilled, unskilled manual and lowest grade occupations.
CSP; socio-professional category; DLQI: Dermatology Life Quality Index; CDLQI: Children’s Dermatology Life Quality Index; ABS-F: Atopic dermatitis Burden Scale-Family; VAS: visual analogue scale. Figures in bold indicate statistical significance at p < 0.05.