TABLE 5.
Phenotypic AMR profilesa of the Klebsiella quasipneumoniae and Escherichia coli recovered from White-tailed deer and their respective transconjugantsb
| Antimicrobial | Klebsiella quasipneumoniae | J53-KPC-2 | E. coli | J53-NDM-5 | J53 |
|---|---|---|---|---|---|
| Amoxicillin/Clavulanic Acid | >32 | >32 | >32 | >32 | 4 |
| Ampicillin | >32 | >32 | >32 | >32 | 2 |
| Azithromycin | >16 | 4 | >16 | >16 | 2 |
| Aztreonam | >16 | 16 | >16 | >16 | ≤2 |
| Cefepime | >16 | 4 | >16 | >16 | ≤1 |
| Cefotaxime | >32 | 4 | >32 | >32 | ≤0.25 |
| Cefoxitin | 32 | 8 | >32 | >32 | 2 |
| Cefazolin | >16 | >16 | >16 | >16 | ≤8 |
| Ceftiofur | >8 | 8 | >8 | >8 | 0.25 |
| Ceftriaxone | >64 | 8 | >64 | >64 | ≤0.25 |
| Doripenem | 1 | 1 | >2 | >2 | ≤0.12 |
| Ertapenem | 2 | 1 | >4 | >4 | ≤0.25 |
| Imipenem | 4 | 2 | >8 | >8 | ≤0.5 |
| Meropenem | ≤1 | ≤1 | >8 | >8 | ≤1 |
| Piperacillin Tazobactam | >64 | 32 | >64 | >64 | ≤4 |
| Ticarcillin Clavulanic Acid | >128 | >128 | >128 | >128 | ≤16 |
| Chloramphenicol | 32 | 8 | 8 | 4 | 8 |
| Nalidixic Acid | 32 | 2 | >32 | 2 | 2 |
| Ciprofloxacin | >4 | ≤0.015 | >4 | ≤0.015 | ≤0.015 |
| Levofloxacin | 4 | ≤1 | >8 | ≤1 | ≤1 |
| Doxycycline | >16 | ≤2 | 16 | 8 | ≤2 |
| Minocycline | >16 | ≤2 | 4 | ≤2 | ≤2 |
| Tetracycline | >32 | ≤4 | >32 | >32 | ≤4 |
| Tigecycline | 4 | ≤0.25 | ≤0.25 | ≤0.25 | ≤0.25 |
| Colistin | ≤0.25 | ≤0.25 | ≤0.25 | ≤0.25 | ≤0.25 |
| Polymyxin B | ≤0.25 | ≤0.25 | ≤0.25 | ≤0.25 | ≤0.25 |
| Gentamicin | >16 | 1 | 1 | 0.5 | 0.5 |
| Streptomycin | >64 | 8 | 64 | >64 | 16 |
| Tobramycin | >8 | 2 | ≤1 | ≤1 | ≤1 |
| Amikacin | ≤4 | ≤4 | ≤4 | ≤4 | ≤4 |
| Sulfisoxazole | >256 | ≤16 | >256 | >256 | ≤16 |
| Trimethoprim Sulfamethoxazole | >4 | ≤0.12 | >4 | >4 | ≤0.12 |
a
Minimum inhibitory concentrations (μg/mL).
b
Phenotypic AMR of the recipient J53 isolate is included as reference.