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. 2001 Apr;67(4):1445–1452. doi: 10.1128/AEM.67.4.1445-1452.2001

FIG. 2.

FIG. 2

Alignment of the L. lactis IO-1, L. lactis NRRL B-4449, and L. lactis 210 XylM sequences with seven galactose mutarotases. GenBank accession numbers for the GalM sequences are as follows: A. calcoaceticus, X03893; S. thermophilus, M38175; E. coli, U13636; H. influenzae, X65934; L. lactis ATCC 7962, U60828; L. lactis MG1363, AJ011653; and Lactobacillus casei, AF005933. Three consensus sequences are indicated above the alignment. Consensus sequence 1 includes residues that are conserved in all 10 mutarotases. Consensus sequence 2 includes residues that are conserved in 8 of 10 mutarotases. Consensus sequence 3 includes residues that are similar in 8 of 10 mutarotases. Residue groupings of consensus sequence 3 are as follows: a, acidic residues (DE); b, basic (HKR); f, aliphatic (AGILV); m, amide (NQ); o, aromatic (FWY); h, hydroxyl (ST); i, imino (P); and s, sulfur (CM). Residues identical to those in IO-1 XylM are boxed.