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In vivo proinflammatory cytokines assay and Histological analysis of AIA rats after treated with DS-RLs/DEX hydrogel and DS-FLs/DEX hydrogel. (A–C) The expression levels of IL-6, IL-1β and TNF-α in joint tissue, *p < .05 vs negative control, #p < .05 vs DS-RLs/DEX hydrogel. HE staining of ankle joints (D) (Scale bars = 200 nm). (E) X-ray images of hind paws.
