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. 2022 Jul 12;12(31):19764–19855. doi: 10.1039/d2ra03081k

Chemical structures of pyridine derivatives 279–287 and their IC50 values against cholinesterase enzymes.

Compound no. Chemical structure IC50 values (µM) References
AChE BChE
279 graphic file with name d2ra03081k-u279.jpg 0.95 278
280 graphic file with name d2ra03081k-u280.jpg 0.23 278
281 graphic file with name d2ra03081k-u281.jpg 0.153 nM 38.6 nM 279
282 graphic file with name d2ra03081k-u282.jpg 52.8 nM 0.828 nM 279
283 graphic file with name d2ra03081k-u283.jpg 153 nM 279
284 graphic file with name d2ra03081k-u284.jpg 828 nM 279
285 graphic file with name d2ra03081k-u285.jpg 0.088 280
286 graphic file with name d2ra03081k-u286.jpg 6.32 281
287 graphic file with name d2ra03081k-u287.jpg 5.58 281