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. 2022 Jul 12;12(31):19764–19855. doi: 10.1039/d2ra03081k

Chemical structures of imidazole derivatives 10–24 and their IC50 values against cholinesterase enzymes.

Compound no. Chemical structure IC50 values (µM) References
AChE BChE
10 graphic file with name d2ra03081k-u10.jpg 177.69 90.20 170
11 graphic file with name d2ra03081k-u11.jpg 274.69 101.20 170
12 graphic file with name d2ra03081k-u12.jpg 5.12 8.63 171
13 graphic file with name d2ra03081k-u13.jpg 9.74 6.59 171
14 graphic file with name d2ra03081k-u14.jpg 16.38 11.44 171
15 graphic file with name d2ra03081k-u15.jpg 19.57 18.08 171
16 graphic file with name d2ra03081k-u16.jpg 0.33 172
17 graphic file with name d2ra03081k-u17.jpg 0.324 173
18 graphic file with name d2ra03081k-u18.jpg 17.3 nM 41.67 nM 174
19 graphic file with name d2ra03081k-u19.jpg 17.3 nM 27.02 nM 174
20 graphic file with name d2ra03081k-u20.jpg 17.32 nM 64.28 nM 174
21 graphic file with name d2ra03081k-u21.jpg 2.02 12.40 175
22 graphic file with name d2ra03081k-u22.jpg 2.05 11.45 175
23 graphic file with name d2ra03081k-u23.jpg 11.8 176
24 graphic file with name d2ra03081k-u24.jpg 8.77 177