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. 2022 Jul 12;12(31):19764–19855. doi: 10.1039/d2ra03081k

Chemical structures of triazole derivatives 114–148 and their IC50 values against cholinesterase enzymes.

Compound no. Chemical structure IC50 values (µM) References
AChE BChE
114 graphic file with name d2ra03081k-u114.jpg >100 µM mL−1 206
115 graphic file with name d2ra03081k-u115.jpg 7.31 µM mL−1 206
116 graphic file with name d2ra03081k-u116.jpg 4.52 207
117 graphic file with name d2ra03081k-u117.jpg 5.31 207
118 graphic file with name d2ra03081k-u118.jpg 114 208
119 graphic file with name d2ra03081k-u119.jpg 104 208
120 graphic file with name d2ra03081k-u120.jpg >350 5.98 209
121 graphic file with name d2ra03081k-u121.jpg 4.89 3.61 210
122 graphic file with name d2ra03081k-u122.jpg 10 6.06 210
123 graphic file with name d2ra03081k-u123.jpg 11.07 61.13 210
124 graphic file with name d2ra03081k-u124.jpg 19.59 66.68 210
125 graphic file with name d2ra03081k-u125.jpg 1.46 µg mL−1 211
126 graphic file with name d2ra03081k-u126.jpg 0.521 212
127 graphic file with name d2ra03081k-u127.jpg 0.055 212
128 graphic file with name d2ra03081k-u128.jpg 27 213
129 graphic file with name d2ra03081k-u129.jpg 6 213
130 graphic file with name d2ra03081k-u130.jpg 0.42 214
131 graphic file with name d2ra03081k-u131.jpg 0.0876 215
132 graphic file with name d2ra03081k-u132.jpg 0.0574 215
133 graphic file with name d2ra03081k-u133.jpg 1.80 216
134 graphic file with name d2ra03081k-u134.jpg 0.059 217
135 graphic file with name d2ra03081k-u135.jpg 6.4 218
136 graphic file with name d2ra03081k-u136.jpg 7.9 218
137 graphic file with name d2ra03081k-u137.jpg 7.3 68.6 219
138 graphic file with name d2ra03081k-u138.jpg 2.06 220
139 graphic file with name d2ra03081k-u139.jpg 0.23 220
140 graphic file with name d2ra03081k-u140.jpg 1.10 220
141 graphic file with name d2ra03081k-u141.jpg 5.41 7.52 221
142 graphic file with name d2ra03081k-u142.jpg 13.75 221
143 graphic file with name d2ra03081k-u143.jpg 26.30 222
144 graphic file with name d2ra03081k-u144.jpg 21.71 >100 223
145 graphic file with name d2ra03081k-u145.jpg 0.259 224
146 graphic file with name d2ra03081k-u146.jpg 0.372 224
147 graphic file with name d2ra03081k-u147.jpg 0.327 224
148 graphic file with name d2ra03081k-u148.jpg 4.78 225