Chemical structures of thiadiazole derivatives 149–168 and their IC₅₀ values against cholinesterase enzymes.

Compound no.	Chemical structure	IC50 values (µM)		References
		AChE	BChE
149		0.351	—	226
150		0.060	—	227
151		0.053	—	227
152		0.344	—	228
153		0.09	—	229
154		0.16	—	229
155		0.77	—	230
156		9.57	—	230
157		18.38	—	231
158		21.91	—	231
159		28.86	—	231
160		2.464	—	232
161		0.189	—	233
162		18.1 nM	—	234
163		0.002	—	235
164		0.006	—	235
165		1.30	—	236
166		1.22	—	236
167		0.029	1.731	237
168		0.074	3.028	237