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. 2022 Jul 12;12(31):19764–19855. doi: 10.1039/d2ra03081k

Chemical structures of pyrrolidine derivatives 169–181 and their IC50 values against cholinesterase enzymes.

Compound no. Chemical structure IC50 values (µM) References
AChE BChE
169 graphic file with name d2ra03081k-u169.jpg 0.10 µmol L−1 238
170 graphic file with name d2ra03081k-u170.jpg 1.57 239
171 graphic file with name d2ra03081k-u171.jpg 1.88 240
172 graphic file with name d2ra03081k-u172.jpg 1.37 240
173 graphic file with name d2ra03081k-u173.jpg 11.84 Pg g−1 241
174 graphic file with name d2ra03081k-u174.jpg 11.3 Pg g−1 241
175 graphic file with name d2ra03081k-u175.jpg 13.7 242
176 graphic file with name d2ra03081k-u176.jpg 21.8 242
177 graphic file with name d2ra03081k-u177.jpg 22.1 242
178 graphic file with name d2ra03081k-u178.jpg 22.9 242
179 graphic file with name d2ra03081k-u179.jpg 24.9 242
180 graphic file with name d2ra03081k-u180.jpg 3.35 5.63 243
181 graphic file with name d2ra03081k-u181.jpg 3.15 4.74 243