Table 1. Mean and standard deviation—behaviour and habenula c-fos immunoreactivity.

Variable	Naive	FOP	CCI
Paw Pressure Test	60.83±5.85	63.33±4.08	30.00±6.12***
Forced Swimming Test	15.50±5.68	19.00±7.75	92.80±27.96***
Open Field Test	731.67±82.80	841.67±145.66	758.00±183.36
Total Habenula	100±12.5	64.5±30.4	55±12*
Total Lateral Habenula	100±8.4	45.7±13.9	33.2±13.8**
Lateral Habenula–Lateral	100±13.2	43.6±16.1	33.4±15.3*
Lateral Habenula—Medial	100±7.4	49.9±12.8	29.4±14.5*
Total Medial Habenula	100±24.8	84.5±40.1	79.9±15.6
Medial Habenula—Superior	100±26.5	222±60.4	454.2±65*
Medial Habenula—Central	100±12.3	82.7±22.8	53.4±5.4***
Medial Habenula—Lateral	100±15.7	76.5±20.7	93.8±8.7
Medial Habenula—Inferior	100±35.9	81.6±8.82	44.0±7.34

Abbreviations: FOP: false-operated, CCI: chronic constriction injury

*p<0.05

**p<0.01

***p<0.001