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. 2022 Jun 17;18(6):e1010507. doi: 10.1371/journal.ppat.1010507

Fig 4. ΔGY and in vivo acquired a.a changes modulate endocytic rates.

Fig 4

(A) Endocytosis of CD4-SIV Env CD chimeras shown in Fig 3A in HeLa cells. (B) Endocytosis of CD4-SIV Env CD constructs containing ΔGY + ΔQTH (YFQL) with the indicated Ala substitutions (SIVmac239 a.a. numbering). Left panels show cell surface CD4 for the indicted times as a % of 0 mins (= 100%); right panels show the rate of endocytosis over the first 5 mins after warming up. Graphs display the mean ± S.E.M. (left) or mean and individual values (right) from ≥ 3 independent experiments.