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. 2022 May 26;13(5):12794–12806. doi: 10.1080/21655979.2022.2071010

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — MicroRNA-145-5p targets and binds to PSAT1. (a) Volcano map of differential mRNAs in normal group and tumor group in colon cancer data set (red for upregulated and green for downregulated); (b) Venn plot of predicted target mRNAs of microRNA-145-5p and differentially up-regulated mRNAs; (c) Pearson correlation analysis of microRNA-145-5p and PSAT1; (d) Relative expression of PSAT1 in TCGA (blue: normal and Orange: tumor); (e) PSAT1 mRNA level in different cell lines; (f) PSAT1 protein level in different cells; (g-h) The effect of overexpressed/silenced microRNA-145-5p on PSAT1 level; (i) The binding of microRNA-145-5p to PSAT1; * denotes p < 0.05.