Table 3.

Toxicities of compounds

Number	Compounds	Mouse NTP		Rat NTP		Ames	DTP
		Female	Male	Female	Male
1	ZINC000014951634	0.089	0	1	0	0	1
2	ZINC000014951658	1	0	1	0	0	1
3	ZINC000028968101	1	0.021	0.06	0.997	1	1
4	ZINC000049872065	0.353	0	0.752	0.006	0	0
5	ZINC000002509755	0.603	0.001	0	0.535	0.996	0.019
6	ZINC000015122022	0	1	1	0	1	1
7	ZINC000002528486	0.603	0.001	0	0.535	0.996	0.019
8	ZINC000001531664	0.999	1	0	1	0	1
9	ZINC000013328774	0.865	1	1	1	0.674	1
10	ZINC000021992902	0.198	0	0.033	0.251	0	0
11	ZINC000030725991	0	0	0.163	1	0	1
12	ZINC000002526388	0.999	0.041	0	0.999	0.999	0.745
13	ZINC000008844372	1	1	1	1	0	1
14	ZINC000013378636	0	1	1	0	1	1
15	ZINC000073280937	0.312	1	0	0.185	0	1
16	ZINC000030730842	1	1	0.001	0	1	0
17	ZINC000006528354	0.151	0	1	0	0.002	1
18	ZINC000044281738	0	0	1	0	0.007	0
19	ZINC000028882432	0.081	1	0	0.987	0	1
20	ZINC000008214697	0	0.003	0	1	0	0
21	Ipatasertib	1	0	0.985	0	0	1

NTP, U.S. National Toxicology Program; DTP, developmental toxicity potential.

NTP<0.3 (noncarcinogen); >0.8 (carcinogen).

Ames<0.3 (nonmutagen); >0.8 (mutagen).

DTP<0.3 (nontoxic); >0.8 (toxic).