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. 2022 Jun 15;13(5):13829–13848. doi: 10.1080/21655979.2022.2084484

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 9. — MiR-490-5p targeted TXNRD1 to exert the anti-tumor role in ESCC cells. KYSE450 and EC109 cells were transfected with miR-NC, miR-490-5p, miR-490-5p + pcDNA, or miR-490-5p + TXNRD1. (a,b) Cell proliferation was evaluated (two-way ANOVA). (c-e) Cell migratory and invasive abilities were determined (two-way ANOVA). (f) Cell apoptosis was detected (two-way ANOVA). (g,h) The expression levels of Bax and Bcl-2 were examined (two-way ANOVA). (i,j) Glucose consumption and lactate production were tested (two-way ANOVA). (k,l) GLUT1 and LDHA protein levels were analyzed (two-way ANOVA). *P< 0.05.