Table 3.

Renal function-related factors associated with tyrosine kinase inhibitor treatment.

Variables	Sorafenib (n = 42)	Lenvatinib (n = 42)	P value
Pretreatment eGFR	73.290 (62.540–79.760)	70.935 (61.840–81.680)	.713
end of treatment eGFR	80.20 (58.60–91.80)	73.00 (51.65–81.35)	.103
Minimum ΔeGFR	−1.840 (−14.180–0.000)	−12.240 (−25.190–-1.350)	.025
ΔeGFR ≤−10% (yes/no)	13/29	23/19	.027
Proteinuria all grade (yes/no)	3/39	13/29	.005
Proteinuria grade ≥3 (yes/no)	1/41	6/36	.049

Data are given as the medians with interquartile range or numbers.

eGFR = estimated glomerular filtration rate.