Table 2.
Factors affecting early treatment response.
Factors | CR | χ 2 | P value |
Age (years) | 0.011 | 1.000 | |
<10 | 26 (89.7) | ||
≥10 | 40 (88.9) | ||
Gender | 1.764 | 0.227 | |
Male | 48 (92.3) | ||
Female | 18 (81.8) | ||
WBC count (×109/L) | 2.926 | 0.132 | |
<100 | 37 (84.1) | ||
≥100 | 29 (96.7) | ||
ETP | 28.856 | <0.001 | |
Yes | 6 (46.2) | ||
No | 57 (98.3) | ||
SIL/TAL1 | 1.804 | 0.473 | |
Negative | 51 (86.4) | ||
Positive | 13 (100) | ||
TCR gene rearrangement | 2.038 | 0.476 | |
Negative | 50 (86.2) | ||
Positive | 14 (100) | ||
WT1 | 1.596 | 0.433 | |
Negative | 30 (93.8) | ||
Positive | 34 (85.0) | ||
CNSL at initial diagnosis | 0.513 | 1.000 | |
Yes | 4 (100) | ||
No | 62 (88.6) | ||
Chemotherapy regimen | 0.561 | 0.711 | |
CCLG-ALL-2008 protocol | 32 (86.5) | ||
Modified BFM protocol | 34 (91.9) |
Data are presented as n (%). ALL: Acute lymphoblastic leukemia; BFM: Berlin-Frankfurt-Muenster; CNSL: Central nervous system leukemia; CCLG-ALL-2008: Chinese Children Leukemia Group-Acute Lymphoblastic Leukemia-2008; CR: Complete remission; ETP: Early T-cell precursor; TCR: T cell receptor; WBC: White blood cell; WT1: Wilms tumor 1 gene.