Table 1.
TREM2 Neuro_Rehabilitation Program: session duration and type of treatment.
| Rehabilitation program | Rehabilitative intervention | Session duration | Type of treatment |
| Step 13 mo(Sep–Nov 2021)Conventional Neurorehabilitation | CCT | 6 weekly sessions of 60 min (72 total treatments) | ROT 15 min: 5 min Temporal Orientation5 min Spatial Orientation5 min Personal Orientation (Emotional/Autobiographical/Motivational Training) |
| APT 20 min: 5 min Visual Research/Selective Attention5 min Alternating Attention5 min Divided Attention5 min Sustained attention | |||
| Memory Training 10 min:5 min Visuo-spatial memory5 min Verbal Memory | |||
| Executive Education Training 15 min10 min Verbal Fluency5 min Categorization | |||
| S-PT | 6 weekly sessions of 60 min (72 total treatments) | Physical Rehabilitation15 min manipulation on muscle tissues, stretching and mobilization in supine position10 min active assisted exercises20 min exercises for trunk control and balance in sitting position/core stability training in supine positionRespiratory Gymnastics10 min Mobilization of the diaphragm muscle5 min Breathing control training | |
| Step 23 mo(Dec 2021–Feb 2022)Combined Rehabilitative Approach | CCT | 3 weekly sessions of 60 min (36 total treatments) | ROT 15 minAPT 20 minMemory Training 10 minExecutive Education Training 15 min (the aforementioned program) |
| Standard Physiotherapy (S- PT) | 3 weekly sessions of 60 min (36 total treatments) | Physical Rehabilitation 35 minRespiratory Gymnastics 25 min (the aforementioned program) | |
| VRRS–Software and Tools dedicate for Cognitive Module | 3 weekly sessions of 60 min (36 total treatments) | ROT 15 minAPT 20 minMemory Training 10 minExecutive Education Training 15 min (the aforementioned program) | |
| VRRS – Software and Tools dedicate for Physical Module | 3 weekly sessions of 60 min (36 total treatments) | Physical Rehabilitation 45 minRespiratory Gymnastics 15 min (the aforementioned program) |
APT = process training, CCT = conventional cognitive training, ROT = reality orientation therapy, S-PT = standard physiotherapy, VRRS = virtual reality rehabilitation system.