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. 2022 May 27;101(21):e29470. doi: 10.1097/MD.0000000000029470

Table 4.

Cognitive outcome evaluated at baseline (T0), after the standard training (T1), at the beginning of the combined experimental approach (T2), and after such approach (T3).

Conventional treatment Advanced treatment VRRS-evo Cogn + PT
Test Domain T0 T1 RCI T2 T3 RCI
MMSE Global Cognition 14.8 12.8 12.8 14.8
CDT Spatial dysfunction and neglect 5 4 4 5
BPRS Psychiatric Symptoms 64 58 60 52 2.1
FCS Functional Communication 27 25 25 30 2.2
FAB Executive Function (verbal and not) 10.9 8.9 7.9 10.9
HRS-D Depression Symptoms 14 20 1.9 19 11 2.1
DRS Disability Category 17 16 17 17
FIM Functional Status 21 19 20 21
TCT Motor/Trunk impairment 24 22 22 26 1.9

BPRS (Brief Psychiatric Rating Scale) range 0–126; CDT (Clock Drawing Test) range 0–10; cut off = 6; DRS (Disability Rating Scale) range 0–29; FAB (Functional Assessment Battery) range 0–18; cut off = 12; FCS (Functional Communication Scale) range 0–22; FIM (Functional Independence Measure) motor (items 1–13): 13–91; cognitive (items 14–18): 5–35; HRS-D (Hamilton Rating Scale for Depression) range 0–24; cut off = 7; MMSE (Mini Mental State Examination) range 0–30; cut off = 24; total (items 1–18): 18–126TCT (Trunk Control Test) range 0–100.