Table 3.

Retrospective cohort comparison of progression to severe COVID-19 between the EBV-positive and EBV-negative groups.

		EBV-negative (n = 224)	P-value
COVID-19 severity	COVID-19 severity	n (%)
Gr1	Gr1	182 (81.3%)
Gr2	Gr2	36 (16.7%)
Gr3	Gr3	6 (2.7%)
Gr4	Gr4	0 (0.0%)
Gr5	Gr5	0 (0.0%)
Gr6	Gr6	0 (0.0%)
Moderate-severe (Gr2–6)	Moderate-severe (Gr2–6)	42 (18.8%)	.04∗
Severe (Gr3–6)	Severe (Gr3–6)	7 (3.1%)	.003∗

EBV = Epstein–Barr virus, Gr1, Grade 1 = symptomatic but no oxygen therapy required, Gr2, Grade 2 = low-flow nasal cannula, Gr3, Grade 3 = high-flow nasal cannula/non-invasive ventilation, Gr4, Grade 4 = mechanical ventilation, Gr5, Grade 5 = extracorporeal membrane oxygenation, Gr6, Grade 6 = death.