Table 1.
Distributions of the ESR1 and ESR2 SNPs in case and control.
| MAF (frequency) | |||||||||
| Genes | SNP ID | Position | Minor Allele | Case | Control | P | P (corrected)a | ORb (95% CI) | Power |
| ESR1 | rs9340799 (A > G) | 6:151842246 | G | 0.203 | 0.252 | .06 | – | 0.68 (0.41–1.12) | 64.8 |
| rs2234693 (T > C) | 6:151842200 | C | 0.412 | 0.392 | .49 | – | 1.14 (0.75–1.75) | ||
| rs3798759 (A > C) | 6:151959418 | C | 0.302 | 0.304 | .94 | – | 1.24 (0.78–1.96) | ||
| ESR2 | rs2077647 (T > G) | 14:151807942 | G | 0.373 | 0.405 | .29 | – | 1.04 (0.67–1.61) | |
| rs4986938 (C > T) | 14:64233098 | T | 0.109 | 0.147 | .07 | – | 0.91 (0.46–1.79) | ||
| rs1256049 (C > T) | 14:64257333 | T | 0.364 | 0.397 | .27 | – | 1.22 (0.79–1.87) | ||
– = not significant, 95% CI = 95% confidence intervals, MAF = minor allele frequency, OR = odds ratio, SNP = single-nucleotide polymorphism.
a
The Bonferroni's correction was carried out to correct the P value.
b
OR and 95% CI are calculated for the minor allele of each SNP.