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. 2022 Feb 15;135(8):920–929. doi: 10.1097/CM9.0000000000002037

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Bio-informatics analysis of NOTCH1-mutated and NOTCH1-wt CLL cells In GSE75122. (A) The heatmap of five NOTCH1-mutated and five NOTCH1-wt CLL samples. (B) KEGG analysis of DEGs whose expressions were upregulated in NOTCH1-mutated CLL samples. (C) GSEA analysis of five NOTCH1-mutated and five NOTCH1-wt CLL samples. (D)The heatmap of genes involved in spliceosome. CLL: Chronic lymphocytic leukemia; DEGs: Differentially expressed genes; GSEA: Gene set enrichment analysis; KEGG: Kyoto Encyclopedia of Genes and Genomes.