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. Author manuscript; available in PMC: 2023 Jun 10.
Published in final edited form as: Clin Infect Dis. 2022 Jun 10;74(11):2082–2083. doi: 10.1093/cid/ciab899

Table 1.

Adverse Events Reported With Use of Diphtheria Antitoxin in the United States, 2004–2019

DAT Amount Administered AE Type Time to AE Following DAT Administration AE Duration Treatment Given Outcome
100 000 IU

  • Fever (maximum temperature, 102.5°F)

  • Maculopapular rash: morbilliform eruption diffusely on the trunk, upper extremities, and lower extremities

  • Skin biopsy of rash: sparse perivascular lymphatic infiltrate (pathology consistent with drug eruption)

 Fever: 90 minutes; rash: 8 days Fever: 1 hour; rash: 4 days Acetaminophen (1 g) Recovered

Abbreviations: AE, adverse event; DAT, diphtheria antitoxin.