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. 2022 Jun 28;9:850929. doi: 10.3389/fnut.2022.850929

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Copyright © 2022 Chen, Chen, Huang, Xu, Zhang, Shi, Cai, Zhang, Li and Shen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Muscle ROI: after the muscle region is labeled in ITK-SNAP software, semi-automatic drawing is adopted to check the psoas major muscle region and 3d reconstruction. (B) Manhattan plot presenting the strength of association –log10 (p-value) of spearman’s rho between the psoas radiomic features and the original sarcopenia (diagnosed by SMI, grip strength and walking speed). (C,D) Model with smallest lambda was selected lambda 0.0451, ln (lambda) –3.098, and 14 features selected from the lasso were included in the subsequent radiomic score model.