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. 2022 Apr 27;395(8):945–962. doi: 10.1007/s00210-022-02243-1

Fig. 3.

Fig. 3

Echocardiographic assessment of LV structural and functional data in rats. ab Echocardiographic representative M-mode and pulse-wave Doppler images to visualize myocardium structure. c Canagliflozin mitigated LV function in HFpEF rats indicated by LVAWd, LV mass corr., E/A, SV, CO, and IVRT. n = 6 rats/group. Data are presented as mean ± standard deviation. *p < 0.05 versus normal group. #p < 0.05 versus HFpEF group. LVAWd, left ventricular anterior wall in diastole; LV mass corr., left ventricular mass corrected; E/A, early diastolic filling to atrial filling velocity ratio of mitral flow; SV, stroke volume; CO, cardiac output; IVRT, isovolumic relaxation time