Table 2.
Animal characteristics and cardiovascular biochemical indicators of rats at the 12th week
| Normal | HFpEF | Cana | P | |
|---|---|---|---|---|
| n = 12 | n = 8 | n = 12 | ||
| Body weight (g) | 384.33 ± 20.94 | 356.70 ± 22.50* | 330.16 ± 18.33*# | < 0.05 |
| LV weight/TL (mg/mm) | 20.14 ± 2.19 | 24.04 ± 2.69* | 20.67 ± 2.52# | 0.004 |
| Creatinine (μmol/l) | 27.53 ± 3.48 | 41.37 ± 5.25* | 32.70 ± 2.90*# | < 0.05 |
| Blood glucose (mmol/l) | 4.6 ± 0.7 | 4.6 ± 0.5 | 4.1 ± 0.6 | 0.106 |
| D3-H (mmol/l) | 1.05 ± 0.07 | 1.06 ± 0.05 | 1.34 ± 0.10# | < 0.05 |
| TC (mmol/l) | 2.83 ± 0.32 | 3.18 ± 0.99 | 3.17 ± 0.33 | 0.335 |
| TG (mmol/l) | 0.49 ± 0.13 | 0.55 ± 0.22 | 0.50 ± 0.14 | 0.627 |
| LDL-c (mmol/l) | 1.58 ± 0.28 | 1.81 ± 0.23 | 1.76 ± 0.42 | 0.252 |
| HDL-c (mmol/l) | 0.55 ± 0.11 | 0.63 ± 0.13 | 0.52 ± 0.08 | 0.098 |
| Insulin (μg/l) | 0.33 ± 0.07 | 0.30 ± 0.02 | 0.30 ± 0.03 | 0.257 |
| BNP (pg/ml) | 201.96 ± 49.66 | 338.65 ± 23.33* | 184.79 ± 56.12# | < 0.05 |
| n = 6 | n = 6 | n = 6 | ||
| Food intake (g/24 h) | 15.22 ± 1.45 | 20.97 ± 1.20* | 25.16 ± 4.46*# | < 0.05 |
| Water intake (ml/24 h) | 19.5 ± 7.9 | 82.8 ± 20.1* | 135.2 ± 20.5*# | < 0.05 |
| Urine volume (ml/24 h) | 9.6 ± 4.4 | 57.2 ± 20.7* | 102.7 ± 5.4*# | < 0.05 |
Data are presented as mean ± standard deviation. *p < 0.05 versus normal group. #p < 0.05 versus HFpEF group. LV weight/TL, left ventricular weight/tibial length; D3-H, 3-hydroxybutyric acid; TC, total cholesterol; TG, triglyceride; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; BNP, brain natriuretic peptide