Table 4.
Enriched metabolic pathways and related proteins
| KEGG pathway | Related proteins | p value |
|---|---|---|
| Ferroptosis | Tfrc, Steap3, Prnp | 0.001492 |
| PPAR signaling pathway | Acox1, Acaa1a, Ehhadh, Plin2, Hmgcs2 | 0.000096 |
| Protein processing in endoplasmic reticulum | Pdia3, Dnajc10, Stt3b, Dnajb11 | 0.013082 |
| Wnt signaling pathway | Serpinf1, Cacybp, Plcb3, Gpc4 | 0.010692 |
| Oxidative phosphorylation | COX2, Cox5b, Cox6a1, Ndufb4 | 0.006973 |
| Peroxisome | Acox1, Acaa1a, Ehhadh | 0.012290 |
| Cardiac muscle contraction | COX2, Cox5b, Cox6a1 | 0.011574 |
| Thermogenesis | COX2, Cox5b, Cox6a1, Ndufb4 | 0.041364 |
| Retrograde endocannabinoid signaling | Plcb3, Ndufb4, Gng10 | 0.049482 |
Related proteins were obtained from differentially expressed proteins between the HFpEF group and the Cana group