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. 2022 Jul 12;12:279. doi: 10.1038/s41398-022-02049-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The plots show the Pearson correlation coefficients for A the combined male and female sample (All), B female-only sample, and C male-only sample. The ellipses are the visualizations for the corresponding Pearson correlation coefficients. Positive correlation is displayed in blue with slope of 1 and negative correlation is in red color with slope of −1. The color intensity and the eccentricity of the ellipse are proportional to the absolute value of correlation coefficient. For Pearson correlation coefficients of 0.1 or greater, CRP was positively correlated for A All subjects with age (r = 0.18), caffeine use (r = 0.05), nicotine use (r = 0.07), body mass index (BMI) (r = 0.49), percent body fat (PBF) (r = 0.45), waist-to-hip ratio (WHR) (r = 0.26), PHQ score (r = 0.13), and QIDS-SR Sleep score (r = 0.15); B Female subjects with age (r = 0.16), caffeine use (r = 0.05), BMI (r = 0.53), PBF (r = 0.54), and WHR (r = 0.30), PHQ (r = 0.09), and QIDS-SR (r = 0.11); and C Male subjects with age (r = 0.24), caffeine use (r = 0.07), nicotine use (r = 0.19), BMI (r = 0.39), PBF (r = 0.40), WHR (r = 0.34), PHQ score (r = 0.18), DAST score (r = 0.15), and QIDS-SR Sleep score (r = 0.21).