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. 2022 Jul 12;12:11732. doi: 10.1038/s41598-022-15216-4

Table 3.

Comparison of maternal and neonatal outcomes, and assessment of relative risks (RR) in women with risk of developing gestational hypertension in Control group and Study group in the perinatal period.

Parameters Control group (n = 113) Study group (n = 121) Relative risk (95% CI) P value
Number (%) Number (%)
Maternal outcomes
Developed HDP 43 (38.1) 8 (6.61) 3.93 (2.06–7.51) 0.001
i. Developed GH 29 (25.66) 29 (25.66) 8 (6.61) 2.65 (1.42–4.95) < 0.001
ii. Developed Preeclampsia 11 (9.73) Nil (0) 0.45 (0.39–0.52) < 0.001
iii. Developed Eclampsia 3 (2.65) Nil (0) 0.47 (0.41–0.54) 0.071
Premature delivery
(< 36 weeks of gestation) 3 (2.65) Nil (0) 0.47 (0.41–0.54) 0.071
Pregnancy complications
IUGR 7 (6.19) 1 (0.82) 4.24 (0.67–26.67) 0.024
PROM 3 (2.65) Nil (0) 0.47 (0.41–0.54) 0.071
Other complications 4 (3.53) Nil (0) 0.47 (0.41–0.54) 0.037
Mode of delivery
SVD 85 (75.22) 117(96.69) 0.21(0.08–0.54) < 0.001
LSCS 25 (22.12) 4 (3.31) 4.13 (1.65–10.35) < 0.001
Instrumental delivery 3 (2.65) Nil (0) 0.47 (0.41– 0.545) 0.071
Duration of labor*
1st stage labor 653.98 ± 128.48 401.48 ± 129.43 < 0.001
2nd stage labor 45.48 ± 13.04 39.29 ± 12.13 0.002
Total duration of labor 699.46 ± 127.77 440.78 ± 129.27 <0.001
Comfort during labor
By Numeric Pain Rating Scale* 6.69 ± 3.68 5.35 ± 1.44 0.003
By Pain Mastery Scale
(i) No Pain Nil (0) Nil (0)
(ii) Manageable pain 3 (2.9) 99 (97.1) 0.17 (0.11–0.25) <0.001
(iii) Bearable pain 31 (63.3) 18 (36.7) 1.51 (1.02–2.23) 0.018
(iv) Unbearable pain 54 (32.8) Nil (0) 0.32 (0.26–0.40) <0.001
Neonatal Outcomes
Birth weight (kg)* 2.76 ± 0.34 2.91 ± 0.35 0.001
< 2.5 kg 14 (12.38) 4 (3.30) 0.41 (0.17–0.98) 0.009
2.5–3.4 kg 99 (87.61) 117 (96.70) 0.41 (0.17–0.98) 0.009
≥ 3.5 kg Nil (0) Nil (0)
APGAR score at 1st min
<7 12 (10.61) 2 (1.76) 3.78 (1.04–13.73) 0.004
≥ 7 101(89.38) 119 (98.34) 3.78 (1.04–13.73) 0.004
APGAR score at 5th min
≥ 7 113 (100) 121 (100)
RDS 3 (2.65) Nil (0) 0.47 (0.41–0.54) 0.071
NICU admission 5 (4.42) Nil (0) 0.47 (0.41–0.54) 0.019

The data are presented as number and percentage. * The duration of labor, assessment of comfort during labor by NPRS (Numeric Pain Rating Scale), and birth weight are expressed in Mean ± SD and comparison of these continuous data was done by independent t test.

P value < 0.05 was considered statistically significant.

HDP hypertensive disorders of pregnancy, GH gestational hypertension, IUGR intrauterine growth retardation, PROM premature rupture of membrane, SVD spontaneous vaginal delivery, LSCS lower segment caesarean section, APGAR appearance, pulse rate, grimace, activity and respiration, RDS respiratory distress syndrome, NICU neonatal intensive care unit.

Numeric pain rating scale ranges from 0 to 10. The scale 0 represents “no pain”, 1 to 3 represents “mild pain”, 4 to 6 represents “moderate pain” and 7 to 10 represents “severe pain”. Pain mastery scale has 4 grading of pain: no pain, manageable pain, bearable pain and unbearable pain.