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. 2022 Jul 11;13(7):593. doi: 10.1038/s41419-022-05026-x

Fig. 2. LSECtin positively regulates GC cell adhesion, proliferation, migration, and invasion in vitro and lymphatic metastasis in vivo.

Fig. 2

A, B Adhesion in vitro between GC cells and frozen mouse lymph node sections was detected by H&E staining (A). Histogram shows quantification analysis of cell number (B). C Adhesion of LSECtin to several GC cells was detected by flow cytometry. D Quantification of the clonogenic assay results after cells were treated with the 5 μg/ml LSECtin protein or control IgG. E, F The migratory and invasive abilities of GC cells treated with the 5 μg/ml LSECtin protein or control IgG were determined by Transwell assay. G The results of wound healing assays after cells were treated with the 5 μg/ml LSECtin protein or control IgG. H Pictures of lymph nodes harvested from nude mice 24 days after injected. I Representative H&E staining showing metastatic nodules and metastatsis rates. Data, the means ± SD (n = 3).