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. 2022 Jul 12;12:11801. doi: 10.1038/s41598-022-15401-5

Table 2.

Correlation of ET-1 level in plasma or AqH to OCT/OCT-A parameters in glaucoma.

Parameter ET1-Plasma [pg/ml] ET1-AqH [pg/ml]
rho (p) rho (p)
Age at surgery 0.256 (0.035) − 0.178 (0.20)
Refractive error 0.264 (0.031) − 0.088 (0.53)
Visual acuity (LogMAR) 0.131 (0.29) − 0.060 (0.67)
IOP − 0.263 (0.030) − 0.020 (0.89)
Cup/disc ratio vertical 0.261 (0.044) 0.029 (0.85)
Disc area 0.370 (0.004) 0.024 (0.87)
ONH Whole − 0.080 (0.52) 0.066 (0.64)
PeriONH TempInf − 0.246 (0.05) 0.201 (0.17)
PeriONH TempSup − 0.348 (0.007) − 0.001 (1.00)
Fovea SVP − 0.323 (0.007) 0.177 (0.20)
Fovea DVP − 0.331 (0.006) 0.204 (0.14)
FAZ 0.256 (0.035) − 0.110 (0.43)
Topical antiglaucoma medications − 0.126 (0.31) 0.374 (0.006)
RNFL Thickness Sup − 0.242 (0.050)* 0.101 (0.48)
RNFL Thickness Inf − 0.089 (0.48) 0.086 (0.55)
OCT GSS score 0.112 (0.38) − 0.042 (0.78)

The p-value p = 0.050* in the table indicates the significance of the corresponding test, that means p < 0.05.

aCorrelation coefficient: Pearson’s rho for bivariate gaussian distributions, otherwise Spearman’s rho.

bCorrelation test: Pearson’s method for bivariate gaussian distributions, otherwise Spearman’s method.