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. 2022 Jul 12;8:25. doi: 10.1038/s41526-022-00206-7

Table 1.

Cardiovascular function and timing intervals through the three phases of bed rest.

Variable BDC12 HDT01 HDT 29 HDT52 R8
Campaign 1 Campaign 2 Campaign 1 Campaign 2 Campaign 1 Campaign 2 Campaign 1 Campaign 2 Campaign 1 Campaign 2
HR (bpm) 55 ± 4 64 ± 8 59 ± 11 55 ± 10 61 ± 13* 63 ± 9* 66 ± 15* 67 ± 11* 71 ± 14* 67 ± 7*†
RR (ms) 917 ± 67 1067 ± 133 983 ± 183 917 ± 167 1017 ± 217* 1050 ± 150* 1100 ± 250* 1117 ± 183* 1183 ± 233* 1117 ± 117*†
SBP(mmHg) 118 ± 13 125 ± 21 104 ± 11* 120 ± 15*† 123 ± 15 132 ± 18 113 ± 15 128 ± 19 116 ± 11 129 ± 21
DBP (mmHg) 63 ± 8 65 ± 7 54 ± 8* 59 ± 7* 66 ± 9 71 ± 12 64 ± 8 71 ± 12 62 ± 5 70 ± 13
MAP (mmHg) 83 ± 10 85 ± 12 71 ± 9 79 ± 10 85 ± 10 91 ± 13 80 ± 9 90 ± 14 80 ± 7 90 ± 15
PTT (ms) 189 ± 29 209 ± 38 123 ± 40* 182 ± 60*† 106 ± 29* 208 ± 31 110 ± 26* 205 ± 36 113 ± 17* 179 ± 45*†
LVET(ms) 337 ± 28 308 ± 35 344 ± 49* 340 ± 21* 320 ± 38 312 ± 20 308 ± 34* 300 ± 20* 310 ± 23* 313 ± 15*

Campaign groups were paired comparing HDBR phases to baseline BDC12. Further unpaired analysis was done to compare Campaign 1 and Campaign 2. Cardiovascular timing intervals were Values are split based on phase and further split based on campaign season. Campaign 1 coincides with the first season started in January and Campaign 2 coincides with the second season started in September. * Denotes significant differences compared to BDC12 and † denotes significance between campaigns at each test day (Two-way ANOVA, p < 0.05).

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