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. 2022 Mar 5;127(1):30–42. doi: 10.1038/s41416-022-01757-y

Fig. 1. METTL14 is low expressed in the ccRCC and correlates with poor prognosis.

Fig. 1

a Total m6A content in the ccRCC tissues. n = 16. b Protein levels of METTL3 in the ccRCC tissues (C1-C8) and the adjacent normal tissues (T1-T8) were detected by western blot. Protein expression levels were analysed by ImageJ densitometric analysis. n = 16. c mRNA levels of METTL3 in the ccRCC tissues and the adjacent normal tissues were detected by qRT-PCR. n = 16. d Protein levels of METTL14 in the ccRCC tissues (C1-C8) and the adjacent normal tissues (T1-T8) were detected by western blot. Protein expression levels were analysed by ImageJ densitometric analysis. n = 16. e mRNA levels of METTL14 in the ccRCC tissues and the adjacent normal tissues were detected by qRT-PCR. n = 16. f Immunochemical staining showed METTL14 expression in tumour tissues. Bar = 400 μm. n = 12. Data are presented as mean ± SEM from three independent experiments. *P < 0.05, **P < 0.01,***P < 0.001, compared to the control group.