Fig. 7. SNHG25 promotes NB tumor growth in vivo through SNORA50C/HDAC1 axis.
Mice were injected with cells transfected with sh-NC, sh-SNHG25#1, or sh-SNHG25#1 + HDAC1, respectively. A–D Representative images of xenografts, tumor size, volume, and weight were shown. (One-way ANOVA, Tukey) E, F RT-qPCR and western blot detected SNORA50C and HDAC1 expression in the xenografts. (One-way ANOVA, Tukey) G The protein expression of HDAC1 and Ki67 was detected by IHC, with the quantitative histograms aside. **P < 0.01. Error bars indicate mean ± SD. (N = 3).