Table 4.
Outcome | GBS after SARS-CoV-2 vaccination (n=70) |
Maximum level of care | |
Outpatient | 4/70 (6%) |
Medical ward | 50/70 (71%) |
High dependency unit | 6/70 (9%) |
Intensive care unit | 10/70 (14%) |
Discharge destination | |
Usual place of residence | 46/70 (66%) |
Medical ward | 9/70 (13%) |
Rehabilitation | 13/70 (18%) |
Died during admission | 2/70 (3%) |
Duration of admission | |
Median (IQR) | 13.5 days (8–28.5; for n=52) |
GBS disability score at 3 months | |
No symptoms (score 0) | 5/59 (9%) |
Symptomatic but able to run (score 1) | 20/59 (34%) |
Able to walk independently, but unable to run (score 2) | 9/59 (15%) |
Mobilising with aids (score 3) | 13/59 (15%) |
Wheelchair bound or bedbound (score 4) | 9/59 (15%) |
Ventilated for at least a part of the day (score 5) | 1/59 (2%) |
Died (score 6) | 2/59 (3%) |
Further SARS-CoV-2 vaccination | |
Yes | 7/70 (10%)* |
Further three patients (two with sensorimotor AIDP and one with facial diplegia with paraesthesias variant) who initially received ChAdOx1 opted to receive BNT162b2 for their second dose. For all, the GBS was classified as probably linked with the vaccine. None had any new symptoms or deterioration.
*Four patients (three with classic sensorimotor AIDP and one with facial diplegia with paraesthesias variant) received a second dose of the same SARS-CoV-2 vaccine after their acute illness. One, whose GBS had been classified as unlikely linked to the vaccine, had a further dose of BNT162b2; one, whose GBS was possibly linked to the vaccine, had ChAdOx1; and two, whose GBS was classified as probably linked, had a further dose of ChAdOx1. None had any new symptoms or deterioration.
AIDP, acute inflammatory demyelinating polyneuropathy.;