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. 2022 Jun 29;13:900254. doi: 10.3389/fimmu.2022.900254

Figure 2.

Figure 2

Diabetes Mellitus promotes the development of atherosclerosis: the role of NLRP3. In the context of diabetes mellitus, risk factors such as high glucose, oxidative stress, and inflammation can induce endothelial dysfunction, inflammation, and platelet activation and aggregation by regulating NLRP3 inflammasome, thereby promoting atherosclerosis.