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. 2022 Jul 13;21:100466. doi: 10.1016/j.lanepe.2022.100466

Table 4.

Relative vaccine effectiveness of the fourth dose against all-cause mortality in individuals aged 80 years and older by number of days after the fourth dose, and according to sex, age, and time passed since vaccination.

Fourth-dose group
Third-dose group
Relative vaccine effectiveness (95% CI)
Deaths Deaths/100,000 person-days Deaths Deaths/100,000 person-days Adjusted for age and baseline date Fully adjusted*
7-60 days, total cohort (N = 365,249) 2040 17·4 2659 45·3 64 (62-66) 71 (69-72)
 Men (N = 151,823) 887 17·9 1195 50·5 67 (65-70) 71 (69-74)
 Women (N = 213,426) 1153 17·0 1464 41·8 62 (59-65) 70 (68-72)
 Age >85 years (N = 186,451) 1520 25·2 1957 66·4 64 (62-67) 71 (69-73)
 Age ≤85 years (N = 178,798) 520 9·1 702 24·0 65 (61-69) 70 (67-74)
 >4 months since vaccination in the third-dose group (N = 134,831) 859 18·5 1353 80·6 78 (77-80) 79 (77-81)
 ≤4 months since vaccination in the third-dose group (N = 230,418) 1181 16·6 1,306 31·2 50 (46-54) 61 (58-64)
 >4 months since vaccination in the fourth-dose group (N = 308,446) 1815 18·3 2298 46·3 63 (61-66) 71 (69-72)
61-143 days, total remaining cohort (N = 243,880) 757 4·8 297 7·8 46 (38-53) 54 (48-60)

CI=confidence interval.

Adjusted for age, baseline date, sex, born in Sweden, and residence in long-term care facility.