Table 4.
Laboratory features of new onset type 1 diabetic children with DKA during pre-pandemic and COVID-19 pandemic period.
| New onset type 1 diabetes | Previously type 1 diabetes | |||||
|---|---|---|---|---|---|---|
| Pre-pandemic (n = 284) | COVID-19 pandemic (n = 305) | p-value | Pre-pandemic (n = 233) | COVID-19 pandemic (n = 175) | p-value | |
| pH | 7.09 (6.95–7.19) | 7.01 (6.91–7.12) | p < 0.001 | 7.10 (6.99–7.19) | 7.05 (6.93–7.16) | p < 0.01 |
| HCO3 | 6.30 (4.50–10.0) | 6.10 (4.60–8.00) | ns | 7.40 (5.30–10.0) | 6.90 (5.20–9.75) | ns |
| pCO2 | 19.6 (15.4–25.0) | 19.0 (15.2–22.7) | ns | 21.5 (17.0–26.0) | 21.0 (16.0–27.0) | ns |
| Lactate | 1.71 (1.23–2.48) | 1.90 (1.40–2.70) | ns | 1.71 (1.23–2.48) | 1.90 (1.40–2.70) | ns |
| Serum glucose (mg/dl) | 470 (377–574) | 471 (400–566) | ns | 467 (369–590) | 456 (370–572) | ns |
| HbA1c | 11.7 (10.2–13.3) | 12.4 (10.9–14.0) | p < 0.001 | 11.9 (10.2–14) | 12.2 (10.8–14.0) | ns |
| Sodium | 132 (129–135) | 132 (130–135) | ns | 133 (130–136) | 134 (131–136) | ns |
| Potassium | 4.08 (3.60–4.50) | 4.04 (3.61–4.43) | ns | 4.80 (4.34–5.30) | 4.80 (4.20–5.31) | ns |
| Blood Urea Nitrogene | 16.0 (11.0–28.0) | 14.0 (10.0–23.0) | ns | 23.0 (16.0–37.0) | 21.0 (14.5–33.0) | ns |
| Creatinine | 0.7 (0.6–0.9) | 0.7 (0.5–0.9) | ns | 0.9 (0.7–1.1) | 0.9 (0.7–1.09) | ns |
| Phosphorus | 3.40 (2.79–4.00) | 4.04 (3.61–4.43) | ns | 3.99 (3.00–5.01) | 4.80 (3.00–5.48) | ns |
| WBC | 14,300 (9,500–22,000) | 15,900 (11,500–23,000) | p < 0.05 | 16,000 (10,300–23,900) | 19,000 (12,700–26,600) | p < 0.01 |
| Absolute neutrophil count (mm3) | 7,400 (4,020–13,300) | 9,600 (5,610–16,600) | p < 0.001 | 10,300 (5,560–17,900) | 13,500 (6,780–19,700) | ns |
| Absolute lymphocyte count (mm3) | 3,250 (2,220–5,950) | 3,180 (2,110–5,540) | ns | 2,690 (1,840–3,860) | 2,760 (2,080–4,650) | ns |
Statistically significant values showed as bold.