Table 2.
Baseline and year-8 characteristics for the four trajectory groups
| Gain | Stable | Steady loss | Steep loss | P | |
|---|---|---|---|---|---|
| Total | 307 (7.7) | 1,581 (39.5) | 1,731 (43) | 380 (9.5) | |
| Baseline | |||||
| Randomization group | <0.0001 | ||||
| DSE | 133 (6.7) | 709 (35.8) | 931 (47.0) | 210 (10.6) | |
| ILI | 174 (8.6) | 872 (43.3) | 800 (39.7) | 170 (8.4) | |
| Age, years | <0.0001 | ||||
| 45–54 | 118 (9.5) | 525 (42.4) | 508 (41.0) | 88 (7.1) | |
| 55–64 | 165 (7.8) | 824 (39.1) | 915 (43.4) | 206 (9.8) | |
| 65–76 | 24 (3.7) | 232 (35.7) | 308 (47.4) | 86 (13.2) | |
| Sex | 0.0017 | ||||
| Female | 190 (8.0) | 878 (37.1) | 1,058 (44.7) | 241 (10.2) | |
| Male | 117 (7.2) | 703 (43.1) | 673 (41.2) | 139 (8.5) | |
| Race/ethnicity | 0.0028 | ||||
| Black | 46 (7.2) | 221 (34.4) | 306 (47.7) | 69 (10.8) | |
| Hispanic | 46 (8.9) | 200 (38.5) | 233 (44.9) | 40 (7.7) | |
| White | 202 (8.1%) | 1,024 (41.2) | 1,029 (41.4) | 232 (9.3) | |
| Other | 13 (3.7) | 135 (38.6) | 163 (46.6) | 39 (11.1) | |
| Obesity | 0.0072 | ||||
| No | 44 (6.8) | 277 (42.7) | 288 (44.4) | 40 (6.2) | |
| Yes | 263 (7.9) | 1,304 (38.9) | 1,443 (43.1) | 340 (10.2) | |
| Diabetes duration, years | 6.52 ± 6.09 | 6.34 ± 5.98 | 6.68 ± 6.64 | 8.01 ± 7.19 | 0.0001 |
| HbA1c, % | 7.25 ± 1.22 | 7.23 ± 1.16 | 7.23 ± 1.16 | 7.27 ± 1.07 | 0.8934 |
| Insulin use | 0.0253 | ||||
| No | 249 (7.6) | 1311 (39.9) | 1434 (43.6) | 296 (9.0) | |
| Yes | 46 (8.1) | 208 (36.8) | 238 (42.1) | 73 (12.9) | |
| Multimorbidity index | <0.0001 | ||||
| 0–1 | 55 (6.3) | 391 (44.9) | 371 (42.6) | 54 (6.2) | |
| ≥2 | 252 (8.1) | 1,190 (38.0) | 1,360 (43.5) | 326 (10.4) | |
| Frailty index | 0.3754 | ||||
| <0.021 | 208 (7.6) | 1,109 (40.3) | 1,188 (43.1) | 250 (9.1) | |
| ≥0.21 | 99 (8.0) | 472 (37.9) | 543 (43.7) | 130 (10.5) | |
| BDI depressive symptoms | 0.4613 | ||||
| <10 | 254 (7.6) | 1,333 (40.0) | 1,434 (43.0) | 311 (9.3) | |
| ≥10 | 53 (8.1) | 242 (36.9) | 292 (44.5) | 69 (10.5) | |
| Year 8 | |||||
| Insulin use | 0.0302 | ||||
| No | 178 (7.5) | 946 (39.9) | 1,040 (43.9) | 205 (8.7) | |
| Yes | 102 (8.5) | 490 (40.7) | 480 (39.8) | 133 (11.0) | |
| Multimorbidity index | 0.0002 | ||||
| 0–1 | 11 (7.2) | 80 (52.3) | 61 (39.9) | 1 (0.7) | |
| ≥2 | 296 (7.7) | 1,501 (39.0) | 1,670 (43.4) | 379 (9.9) | |
| Frailty index | <0.0001 | ||||
| <0.21 | 163 (7.8) | 897 (42.7) | 889 (42.3) | 152 (7.2) | |
| ≥0.21 | 144 (7.6) | 684 (36.0) | 842 (44.3) | 228 (12.0) | |
| BDI depressive symptoms | 0.0003 | ||||
| <10 | 238 (7.1) | 1,365 (40.7) | 1,442 (43.0) | 308 (9.2) | |
| ≥10 | 64 (10.8) | 197 (33.3) | 265 (44.8) | 66 (11.2) |
Data are presented as n (%) or mean ± SD. Percentages are n for trajectory group divided by total N for the row.