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The anatomy and function model of the GS in pathophysiology conditions of sICH. The PVS is enlarged after intracerebral haemorrhage. Abundant proinflammatory cytokines and neurotoxic solutes accumulate in the brain parenchyma secondary to haemorrhage, and the clearance rate of GS is decreased. GS: glymphatic system; sICH: spontaneous intracerebral haemorrhage; EPVS: enlarged perivascular space.
