Table 1.
N | Age at Death | Cause of Death | Hardy Scale | Time to Autopsy (in days) | Ventilation |
---|---|---|---|---|---|
1 | 24+3 weeks GA | Intrauterine fetal demise and growth retardation, placental insufficiency | 3 | 3, 2 | No |
2 | 30+2 weeks GA | Intrauterine fetal demise, placental infarction | 3 | 3, 2 | No |
3 | 39+3 weeks GA | Intrauterine fetal demise of unknown cause | 3 | 0, 8 | No |
4 | 1 day | Pulmonary hypertension with alveolar-capillary dysplasia and large-vessel misalignment | 0 | 0, 9 | Yes |
5 | 9 days | Alveolar-capillary dysplasia without misalignment | 0 | 0, 7 | Yes |
6 | 2 months | Intracerebral hemorrhage | 0 | 0, 8 | Yes |
7 | 5 months | Positional asphyxia | 2 | 0, 8 | No |
8 | 7 months | Hypoxic ischemic encephalopathy | 3 | 0, 5 | No |
9 | 22 months | Myocarditis | 0 | 0, 7 | Yes |
10 | 2 years | Intracerebral hemorrhage | 0 | 1, 6 | Yes |
11 | 2 years | Myocarditis with gastroenteritis | 3 | 3, 1 | No |
12 | 5 years | Rhabdomyolysis (LPIN1 mutation) | 0 | 0, 5 | Yes |
13 | 11 years | Osteosarcoma | 4 | 0, 6 | No |
14 | 16 years | Myocarditis | 3 | 0, 1 | No |
15 | 18 years | Myocarditis | 0 | 0, 5 | Yes |
16 | 23 years | Metastasized testicular seminoma | 0 | 2, 3 | Yes |
17 | 24 years | Acute myeloid leukemia | 0 | 0, 1 | Yes |
18 | 26 years | Drug overdose | 3 | 1, 8 | No |
19 | 26 years | Myocarditis | 3 | 2, 5 | No |
20 | 28 years | Drug overdose | 3 | 1, 8 | No |
Abbreviation: GA: gestational age.
Hardy scale: (1) Violent and fast death (terminal phase < 10min); (2) fast death of natural causes (terminal phase estimated at < 1 hr); (3) intermediate death after a terminal phase of 1 to 24; (4) slow death after a long illness, with a terminal phase longer than 1 day; (0) ventilator case, all cases on a ventilator preceding death. (GTEx Consortium. Hardy scale description. [cited 6 Dec 2021]. Available: https://www.ncbi.nlm.nih.gov/projects/gap/cgi-in/variable.cgi?study_id=phs000424.v4.p1&phv=169092#:∼:text=Deathclassificationbasedonthe,phaseestimatedat%3C10min).