Table 1.
List of Decedents with Pre-Existing Condition(s) in the Medical History, Predisposing them to Streptococcal Infection (n = 24).
| Age | Sex | SSs | Immediate COD | Underlying COD/Pre-Existing Medical condition(s) |
|---|---|---|---|---|
| 1m | F | SAg | Sepsis. Meningitis | Ex-preterm infant. Never left hospital |
| 5m | F | SBo | Sepsis | Splenic hypoplasia. s/p cardiac surgery |
| 6m | M | SPn | Sepsis | Volvulus with bowel infarction. s/p partial colectomy |
| 6m | M | SPn | Pneumonia | Ex-preterm infant. Severe brain injury |
| 13 m | F | SPn | Sepsis. Pneumonia | Neuroblastoma. s/p chemotherapy and surgery |
| 13 m | M | SPy | Sepsis. Endocarditis | Congenital heart disease |
| 18 m | M | SPn | Herniation. Meningitis | Ex-preterm child. Spastic diplegia. Recurrent brain infections |
| 2y | M | SPn | Sepsis | Sickle cell disease with multiple crisis episodes |
| 2y | F | SPn | Pneumonia | Down syndrome. Congenital heart disease |
| 3y | F | SPy | STSS | Bilateral congenital chylothoraces |
| 3y | F | SPy | Pneumonia | Glottic/subglottic web. S/p laser surgery |
| 3y | M | SPn | Subacute endocarditis | Supravalvular aortic stenosis. Williams syndrome |
| 4y | M | SVi,SPn | Sepsis. Neutropenic colitis | Chronic constipation. Neurodevelopment disorder (NOS) |
| 5y | F | SPy a | Sepsis. Aspiration pneumonia | Severe central nervous system deficit (NOS). GERD. |
| 5y | M | SVi | Sepsis. Pneumonia | Poor state of hygiene. Prolonged starvation |
| 10y | F | SPy | Sepsis | Klippel-Trenaunay syndrome. Open skin defects overlying vascular malformation |
| 10y | M | SPn | Pneumonia | Progressive neurological deterioration of unknown etiology. Seizures |
| 11y | F | SPy | Meningitis | Systemic juvenile rheumatoid arthritis (on prednisolone) |
| 12y | M | SPy | Sepsis. Pneumonia | Asthma. Eczema |
| 13y | F | SPy | Septic and hemorrhagic shock | Chronic transplant liver failure. Hepatopulmonary syndrome |
| 14y | SVia | Sepsis. Aspiration pneumonia | Cerebral palsy. Spastic quadriplegia | |
| 14y | F | SPn | Sepsis | Down syndrome. Asplenia |
| 14y | M | SAg | Sepsis | Congenital heart disease. s/p cardiac surgeries. Secondary hepatic fibrosis |
| 15y | F | SPy | Sepsis. Suppurative bronchiolitis and bronchitis | Congenital heart disease. s/p cardiac surgeries. Protein losing enteropathy |
COD, cause of death; m, month(s); y, year(s); F, female; M, male; STSS, Streptococcal toxic shock syndrome; NOS, not otherwise specified; GERD, gastro-esophageal reflux disease; s/p, status post; SSp, Streptococcus species; SPn, S. pneumoniae; SPy, S. pyogenes; SAg, S. Agalactiae; SVi, Viridans Str; SBo, S. Bovis.
acontamination.