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. 2022 Jun 29;13:895696. doi: 10.3389/fphar.2022.895696

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Copyright © 2022 You, Wu, Li, Sheng, Zhou and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GDPD4-2 was up-regulated in PCa tissues and cells, which was related to the treatment of herb pair Astragalus IV -PESV. (A) Volcano plot showed the lncRNA expression. (B) The differential lncRNA expression in RWPE-1 and LNCaP cells, *p < 0.05 vs. RWPE-1 group. (C) The differential lncRNA expression was analyzed by RT-qPCR in LNCaP cells after treatment with Astragaloside IV-PESV. *p < 0.05 vs. control group, #p < 0.05 vs. Astragaloside IV group, &p < 0.05 vs. PESV group.